What causes runner’s high? | QI – BBC

what are the chemicals called which give you a high after exercising ah Josh MDMA love it endorphins [Music] oo oh turns out I was closer to the answer than you what are you going to say endorphin I was going to say endorphins yeah so give her one then I thought that was a general instruction to me to give them thing as I’ve had one goad so they did a couple of studies in the 1970s and that showed that exercise increases the level of endorphins in the blood right and that explained the runners High the trouble is that endorphins cannot cross the barrier between the blood and the brain and that means it cannot affect our mood so there had to be something else that caused the runners high so they did another study and they blocked endorphin receptors in people but found that their mood still improved exising is it being smug is that what it is it’s smug it’s smugness it’s the smug hormone it suggested there was another chemical which was the culprit so exercise also increases the levels of endocannabinoids in the blood and cannaboids are canabo are they related to Canabis I’ve heard of this Canabis I’ve heard of this Canabis it’s the psychoactive ingredient in cannabis and it’s like a bliss molecule that is created and when they blocked cannaboid receptors bear in mind this is mice right like this may not work for us but basically they didn’t get an improvement in either mood or pain relief why were mice doing half marathons I mean a half marathon for a mouse is probably quite a long way isn’t it I was once beaten on the line of a half marathon by a man dressed as a clown in a cardboard car cuz I was going I think I’m just pretty well at this and another a man just the clown the whole carbo car around him yeah sprinted past me I was actually once beaten to the line by a goad what yeah there was a man running for testicular cancer and he had a very apt costume and it it bounced across the line before me so yeah if if it’s a photo finish with you and a gon yeah it’s going to win every time it’s going to win cuz it’s got the like too much gonad I mean I’ve got quite a strong profile but it wasn’t enough to beat a goad also it can roll downhills

@ all my friends who signed up for the London Marathon 😂 #QI #iplayer

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